刊名:Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
出版年:2017
出版时间:15 February 2017
年:2017
卷:173
期:Complete
页码:418-424
全文大小:804 K
卷排序:173
文摘
Berberine binds to nucleosomes with higher affinity than DNA. The interaction between berberine and nucleosomes is positive cooperative and spontaneous. Berberine quenches with globular core domain of histone H1 and nucleosomes chromophores reducing fluorescence intensity. Histone H1 is introduced as a new binding site for berberine in chromatin structure.