Protection against fine particle-induced pulmonary and systemic inflammation by omega-3 polyunsaturated fatty acids

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• 作者：Xiang-Yong Li^a ; ^b ; Lei Hao^a ; Ying-Hua Liu^a ; Chih-Yu Chen^a ; Victor J. Pai^a ; Jing X. Kang^a ; ^{kang.jing@mgh.harvard.edu}
• 关键词：Fine particulate matter ; Pulmonary inflammation ; Systemic inflammation ; Oxidative stress ; Omega-3 fatty acids ; Nutritional intervention
• 刊名：Biochimica et Biophysica Acta (BBA) - General Subjects
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：1861
• 期：3
• 页码：577-584
• 全文大小：1747 K
• 卷排序：1861

文摘

Inhaled fine particles are visibly shown to penetrate into multiple organs. Fine particle exposure induces pulmonary and systemic inflammation. Enriched tissue omega-3 levels prevent against particle-induced inflammation. Dietary omega-3 supplementation ameliorates particle-induced inflammation. Increasing omega-3 intake could help manage pollution-related health problems.