Spontaneous intracranial hypotension syndrome: Contribution of radioisotope cisternography

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• 作者：J.P. Suá ; rez^a ; ^{juanpablosuarez@yahoo.es} ; M.L. Domí ; nguez^a ; M.A. Gó ; mez^a ; J.L. Muñ ; oz^b
• 关键词：Intracranial hypotension ; Cerebrospinal fluid leak ; Radioisotope cisternography
• 刊名：Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)
• 出版年：2017
• 出版时间：January-February 2017
• 年：2017
• 卷：36
• 期：1
• 页码：48-52
• 全文大小：3825 K
• 卷排序：36

文摘

Spontaneous intracranial hypotension is a clinical syndrome caused by a loss of cerebrospinal fluid volume, usually secondary to leaking through structural defects of the spinal dura mater. Radioisotope cisternography (RC) can confirm the diagnosis of spontaneous intracranial hypotension, especially in doubtful or atypical case presentations. A retrospective study was conducted on 8 patients who underwent RC because spontaneous intracranial hypotension was suspected, and they presented with atypical clinical manifestations and/or inconclusive findings in other imaging techniques. RC detected paradural extravasation of cerebrospinal fluid in 7 patients. Moreover, there was indirect evidence of cerebrospinal fluid leaks in all 8 patients (early appearance of radioactivity in the bladder, soft tissue uptake of radioisotope and/or reduction in the amount of radiotracer in the brain at 24 h). RC had a significant impact on the diagnosis of 6 patients, and on the therapeutic management of 4 patients.