Pramipexole pretreatment attenuates myocardial ischemia/reperfusion injury through upregulation of autophagy
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- 作者：Yingli Moa ; b ; 1 ; yinglimo@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Lu Tangc ; d ; 1 ; broycn@live.com" class="auth_mail" title="E-mail the corresponding author ; Yi Mae ; mayimayizmc@126.com" class="auth_mail" title="E-mail the corresponding author ; Saizhu Wua ; saizhuwuphd@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Pramipexole ; Myocardial ischemia/reperfusion injury ; Autophagy
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：13 May 2016
- 年：2016
- 卷：473
- 期：4
- 页码：1119-1124
- 全文大小：1214 K
文摘
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Pramipexole pretreatment ameliorated myocardial injury in a mouse I/R model.
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Pramipexole pretreatment alleviated H/R injury in cultured H9c2 cells.
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Pramipexole caused cardioprotection following myocardial ischemia-reperfusion injuries by antioxidants and enhanced autophagy.