Facile synthesis of 3-substituted isoindolinones

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• 作者：Zainab Al-Jaroudi ; Prabhu P. Mohapatra ; Amitabh Jha ; ^{ajha@acadiau.ca" class="auth_mail" title="E-mail the corresponding author}
• 关键词：N-Aryl-3-hydroxyisoindolinones ; Alkyl aryl ketones ; Lewis acid ; Isoindolinones ; N-Acyliminium ion ; Mannich reaction
• 刊名：Tetrahedron Letters
• 出版年：2016
• 出版时间：17 February 2016
• 年：2016
• 卷：57
• 期：7
• 页码：772-777
• 全文大小：3197 K

文摘

The reactions of N-aryl-3-hydroxyisoindolinones and alkyl aryl ketones under Lewis acid-catalyzed anhydrous conditions afforded the corresponding substituted isoindolinones in good to excellent yields.