To Cut or Not to Cut: Discovery of a Novel Regulator of DNA Break Resection

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• 作者：James M. Daley¹ ; ^{james.daley@yale.edu" class="auth_mail" title="E-mail the corresponding author} ; Patrick Sung¹
• 刊名：Molecular Cell
• 出版年：2016
• 出版时间：4 February 2016
• 年：2016
• 卷：61
• 期：3
• 页码：325-326
• 全文大小：236 K

文摘

Nucleolytic resection of DNA double-strand breaks is the crucial first step in their repair via homologous recombination. New findings by id="bbib8">Tkáč et al. (2016) published in this issue of Molecular Cell identify HELB as a novel, cell-cycle-specific negative regulator of DNA end resection.