Characteristics of hypertension subtypes and treatment outcome among elderly Korean hypertensives

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• 作者：Suk-Won Choi ; MD^a ; Min-Kyu Kim ; MD ; PhD^a ; Seong-Woo Han ; MD ; PhD^b ; Sung Hea Kim ; MD^c ; Hyun Joong Kim ; MD ; PhD^c ; Seok-Min Kang ; MD ; PhD^d ; Dae-Kyeong Kim ; MD ; PhD^e ; Byung Soo Kim ; MD^f ; Won Ho Kim ; MD ; PhD^g ; Jang-Young Kim ; MD ; PhD^h ; Hee-Yeol Kim ; MD ; PhDⁱ ; Jay-Young Rhew ; MD^j ; Keum-Soo Park ; MD ; PhD^k ; Kyoung-Im Cho ; MD ; PhD^l ; Myung Ho Jeong ; MD ; PhD^m ; Yong Suk Jeong ; MDⁿ ; Kyu-Hyung Ryu ; MD ; PhD^a ; ^{khryumd@hanmail.net" class="auth_mail} ; on behalf of the investigators of Korean Registry on the Antihypertensive Treatment Patterns in the Elderly ; Hypertension In elderly patienTs [HIT] study
• 关键词：Elderly ; isolated systolic hypertension ; hypertension awareness
• 刊名：Journal of the American Society of Hypertension
• 出版年：April, 2014
• 年：2014
• 卷：8
• 期：4
• 页码：246-253
• 全文大小：363 K

文摘

There are limited data about characteristics of hypertension subtypes in Asian hypertensive patients and their impacts on treatment of hypertension. This prospective, multi-center, observational study evaluated 2439 hypertensive patients. (鈮?0聽years) Inadequately controlled and drug-na茂ve patients were categorized into three hypertension subtypes (isolated systolic hypertension [ISH], combined systolic/diastolic hypertension [SDH], and isolated diastolic hypertension [IDH]), and proportions of each hypertension subtype were evaluated. After 6-month strict treatments, we compared the characteristics of patients who did not achieve target BP with those who did. In overall population, ISH was the most common subtype (53.2%; 1297/2439). However, in drug-na茂ve patients, SDH was the predominant hypertension subtype (59.6%; 260/436). Notably, the proportion of ISH was substantially lower than previously known data. Predictors associated with failure of reaching target BP were old age (>70聽years), hypertension awareness, and baseline systolic blood pressure (鈮?60聽mm Hg) for total patients. In drug na茂ve patients, hypertension awareness, ISH, and microalbuminuria were associated with treatment failure. These findings might have an impact on the evaluations and antihypertensive treatments of elderly Korean patients.