Azomethine ylide mediated inversion of configuration of quaternary imidazoline carbon: converting trans- to its cis-imidazolines

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• 作者：Ke Qu^a ; Jason S. Fisk^a ; Jetze J. Tepe ; ^a ; ^{tepe@chemistry.msu.edu"" rel=""nofollow}
• 关键词：Cancer treatment ; Azomethine ylide ; Imidazoline ; Oxazolone
• 刊名：Tetrahedron Letters
• 出版年：2011
• 出版时间：21 September 2011
• 年：2011
• 卷：52
• 期：38
• 页码：4840-4842
• 全文大小：1344 K

文摘

An efficient synthetic methodology of converting trans-4,5-diaryl-2-imidazolines to the corresponding cis-4,5-diaryl-2-imidazolines has been developed. This methodology features mild reaction conditions and a simple one-pot two-step procedure.