Ganoderma lucidum polysaccharides encapsulated in liposome as an adjuvant to promote Th1-bias immune response
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- 作者：Zhenguang Liu ; Jie Xing ; Sisi Zheng ; Ruonan Bo ; Li Luo ; Yee Huang ; Yale Niu ; Zhihua Li ; Deyun Wang ; dywang@njau.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Yuanliang Hu ; Jiaguo Liu ; Yi Wu
- 关键词：Ganoderma lucidum polysaccharides ; Liposome ; Immune response ; OVA
- 刊名：Carbohydrate Polymers
- 出版年：2016
- 出版时间：20 May 2016
- 年：2016
- 卷：142
- 期：Complete
- 页码：141-148
- 全文大小：1662 K
文摘
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GLPL/OVA were able to maintain good colloidal stability and higher OVA-EE when stored at 4 °C.
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GLPL/OVA could induce more powerful antigen-specific immune responses.
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GLPL/OVA generate a stronger Th1-biased immune response.
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The strong immune response of GLPL/OVA might be attributed to efficient activation and mature of DC in draining lymph nodes.
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