Effect of C-5 position on the photochemical properties and phototoxicity of antofloxacin and levofloxacin: A stable and transient study
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- 作者：Jianfeng Zhaoa ; c ; Yancheng Liua ; Xingxing Jiangb ; c ; Ping Guoa ; c ; Yulie Xua ; c ; Peng Zhanga ; Tianyi Jia ; d ; Zheshuai Linb ; zslin@mail.ipc.ac.cn" class="auth_mail" title="E-mail the corresponding author ; Wenfeng Wanga ; wangwenfeng@sinap.ac.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Antofloxacin ; Levofloxacin ; Laser flash photolysis ; C-5 position ; Phototoxicity
- 刊名：Journal of Photochemistry and Photobiology B: Biology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：155
- 期：Complete
- 页码：122-129
- 全文大小：1121 K
文摘
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Displaying the different phototoxic behaviors of antofloxacin and levofloxacin
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Using DFT method to calculate the lowest singlet energy of these two chemicals
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A reasonable diagram showing the decay pathways of singlets of is proposed.
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Revealing the role of the substituents in C-5 position