The Candida albicans fimbrin Sac6 regulates oxidative stress response (OSR) and morphogenesis at the transcriptional level
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- 作者：Bing Zhang ; Qilin Yu ; Yuzhou Wang ; Chenpeng Xiao ; Jianrong Li ; Da Huo ; Dan Zhang ; Chang Jia ; Mingchun Li ; nklimingchun@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Actin cytoskeleton ; Fimbrin ; Oxidative stress response ; Morphogenesis ; Candida albicans
- 刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：1863
- 期：9
- 页码：2255-2266
- 全文大小：1857 K
文摘
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SAC6 encodes the actin bundling protein fimbrin in C. albicans.
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Sac6 highly affects oxidative stress tolerance.
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Sac6 regulates OSR by affecting cytoplasm-to-nucleus transport of Cap1.
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Sac6 regulates transcription of morphogenesis-related genes.
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Sac6 is involved regulation of secretion and pathogenicity of C. albicans.