Rhodamine based colorimetric and fluorescent probe for recognition of nucleoside polyphosphates through multi-hydrogen bond
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- 作者：Jichuan Kong ; Cheng He ; Xiaolin Zhang ; Qingtao Meng ; Chunying Duan
- 关键词：Chemosensor ; Nucleoside ; Colorimetric and fluorescent ; Naphthyridine ; Rhodamine B ; Cell imaging
- 刊名：Dyes and Pigments
- 出版年：February, 2014
- 年：2014
- 卷：101
- 期：Complete
- 页码：254-260
- 全文大小：1608 K
文摘
A novelty rhodamine B based chemosensor containing 2-amino-7-methyl-1, 8-naphthyridine moiety was designed and synthesized for colorimetric and fluorescent response on corresponding nucleoside polyphosphates through multi-hydrogen bond interaction in aqueous solution. The supramolecular recognition between the RBS and Cytidine-5鈥?diphosphate disodium hydrate (CDP) was investigated carefully: 1H nuclear magnetic resonance confirmed that the formation of multi-hydrogen bonds between naphthyridine moiety and the nucleoside base group could untie the spiro structure of RBS, and the ESI-MS spectra proved the formation of the 1:1 complexation species between RBS and CDP. The strong emission response of the RBS toward CDP and Adenosine-5鈥?triphosphate disodium trihydrate (ATP) ensures its application in living cells imaging.