Facile synthesis of manganese ferrite/graphene oxide nanocomposites for controlled targeted drug delivery
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- 作者：Guangshuo Wang ; wgs8136@163.com" class="auth_mail" title="E-mail the corresponding author ; Yingying Ma ; Lina Zhang ; Jingbo Mu ; Zhixiao Zhang ; Xiaoliang Zhang ; Hongwei Che ; Yongmei Bai ; Junxian Hou
- 关键词：Graphene oxide ; Manganese ferrite ; Nanocomposites ; Sonochemical synthesis ; Controlled drug delivery
- 刊名：Journal of Magnetism and Magnetic Materials
- 出版年：2016
- 出版时间：1 March 2016
- 年：2016
- 卷：401
- 期：Complete
- 页码：647-650
- 全文大小：1371 K
文摘
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Manganese ferrite/graphene oxide (MnFe2O4/GO) were prepared by a facile sonochemical method.
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GO nanosheets were fully exfoliated and decorated homogeneously with MnFe2O4 nanoparticles.
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MnFe2O4/GO exhibited superparamagnetic behavior with saturation magnetization of 34.9 emu/g.
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The in vitro cytotoxicity testing showed negligible cytotoxicity of the obtained MnFe2O4/GO.
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Drug loading capacity was as high as 0.97 mg/mg and drug release showed pH-sensitive feature.