Diacylglycerol Guides the Hopping of Clathrin-Coated Pits along Microtubules for Exo-Endocytosis Coupling
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- 作者：Tianyi Yuan1 ; 2 ; 7 ; Lin Liu1 ; 2 ; 7 ; Yongdeng Zhang3 ; 7 ; Lisi Wei1 ; 2 ; 7 ; Shiqun Zhao1 ; 2 ; Xiaolu Zheng1 ; 2 ; Xiaoshuai Huang1 ; 2 ; Jerome Boulanger4 ; Charles Gueudry5 ; 6 ; Jingze Lu3 ; Lihan Xie1 ; 2 ; Wen Du3 ; Weijian Zong1 ; 2 ; Lu Yang1 ; 2 ; Jean Salamero4 ; 5 ; Yanmei Liu1 ; 2 ; yanmeiliu@pku.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Liangyi Chen1 ; 2 ; lychen@pku.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 刊名：Developmental Cell
- 出版年：2015
- 出版时间：12 October 2015
- 年：2015
- 卷：35
- 期：1
- 页码：120-130
- 全文大小：3137 K
文摘
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Pre-formed CCPs hop to nascent fusion sites to couple endocytosis with exocytosis
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Cortical microtubules anchored on the plasma membrane provide tracks for CCP hopping
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Local, transient diacylglycerol gradients guide the direction of CCP hopping
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Coupled endocytosis mediates rapid clearance of fusion sites for sustained exocytosis