The memory-enhancing effect of erucic acid on scopolamine-induced cognitive impairment in mice
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- 作者：Eunji Kima ; b ; Hae Ju Kod ; Se Jin Jeona ; b ; Sunhee Leea ; b ; Hyung Eun Leea ; b ; Ha Neul Kima ; b ; Eun-Rhan Wood ; Jong Hoon Ryua ; b ; c ; jhryu63@khu.ac.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Erucic acid ; Cognitive function ; Phosphatidylinositide 3-kinase ; Protein kinase C zeta ; Extracellular signal-regulated kinase ; cAMP response element-binding protein
- 刊名：Pharmacology Biochemistry and Behavior
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：142
- 期：Complete
- 页码：85-90
- 全文大小：626 K
文摘
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Erucic acid enhanced cognitive performance of mice with scopolamine-induced deficits.
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Erucic acid activated the signaling pathway of PI3K–Akt–PKCζ–ERK–CREB.
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Erucic acid would be a therapeutic potential for the treatment of cognitive impairment such as AD.
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