Data of methylome and transcriptome derived from human dilated cardiomyopathy

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• 作者：Bong-Seok Jo^a ; In-Uk Koh^b ; Jae-Bum Bae^b ; Ho-Yeong Yu^b ; Eun-Seok Jeon^c ; Hae-Young Lee^d ; Jae-Joong Kim^e ; Murim Choi^f ; Sun Shim Choi^a ; ^{schoi@kangwon.ac.kr}
• 关键词：Methylome ; Transcriptome ; DMP ; DEG ; DCM
• 刊名：Data in Brief
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：9
• 期：Complete
• 页码：382-387
• 全文大小：1024 K
• 卷排序：9

文摘

Alterations in DNA methylation and gene expression have been implicated in the development of human dilated cardiomyopathy (DCM). Differentially methylated probes (DMPs) and differentially expressed genes (DEGs) were identified between the left ventricle (LV, a pathological locus for DCM) and the right ventricle (RV, a proxy for normal hearts). The data in this DiB are for supporting our report entitled “Methylome analysis reveals alterations in DNA methylation in the regulatory regions of left ventricle development genes in human dilated cardiomyopathy” (Bong-Seok Jo, In-Uk Koh, Jae-Bum Bae, Ho-Yeong Yu, Eun-Seok Jeon, Hae-Young Lee, Jae-Joong Kim, Murim Choi, Sun Shim Choi, 2016) [1].