Dietary guanidinoacetic acid increases brain creatine levels in healthy men

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• 作者：Sergej M. Ostojic ; M.D. ; Ph.D.^a ; ^b ; ^{Sergej.ostojic@chess.edu.rs} ; Jelena Ostojic ; Ph.D.^c ; Patrik Drid ; Ph.D.^a ; Milan Vranes ; Ph.D.^d ; Pavle Jovanov ; Ph.D.^e
• 关键词：Cerebellum ; Gray matter ; White matter ; Creatine synthesis ; MR spectroscopy ; Side effects
• 刊名：Nutrition
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：33
• 期：Complete
• 页码：149-156
• 全文大小：1956 K
• 卷排序：33

文摘

Guanidinoacetic acid (GAA) is an experimental dietary supplement and alternative creatine source. Dietary GAA increased brain creatine ≤19.1% after 8 wk supplementation in healthy men. GAA loading was accompanied by impaired methylation profiles in the circulation and brain