刊名:International Journal of Radiation Oncology*Biology*Physics
出版年:2007
出版时间:1 October 2007
年:2007
卷:69
期:2
页码:475-482
全文大小:720 K
文摘
Ankyloglossia (tongue-tie) is a congenital anomaly with a prevalence of 4–5 % and characterized by an abnormally short lingual frenulum. For unknown reasons the abnormality seems to be more common in males. The pathogenesis of ankyloglossia is not known. The author reports a family with isolated ankyloglossia inherited as an autosomal dominant trait. The identification of the defective gene(s) causing ankyloglossia might reveal novel information on the craniofacial embryogenesis and its disorders.