Influence of functional polymorphisms in DNA repair genes of myelodysplastic syndrome
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- 作者：Howard Lopes Ribeiro Juniora ; b ; howard.lrj@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Allan Rodrigo Soares Maiaa ; b ; allanrsm@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Marí ; lia Braga Costaa ; b ; mariliabraga20@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Izabelle Rocha Fariasa ; b ; izabellefarias27@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Daniela de Paula Borgesa ; b ; dpborges0@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Roberta Taiane Germano de Oliveiraa ; b ; tayaneoliveira.g@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Juliana Cordeiro de Sousaa ; b ; cordeiro.juliana@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Silvia Maria Meira Magalhã ; esa ; b ; silviamm@ufc.br" class="auth_mail" title="E-mail the corresponding author ; Ronald Feitosa Pinheiroa ; b ; c ; ronaldfpinheiro@uol.com.br" class="auth_mail" title="E-mail the corresponding author ; ronaldpinheiro@pq.cnpq.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Double-strand DNA breaks ; DNA repair mechanisms genes ; Gene polymorphisms ; Gene expression ; Myelodysplastic syndrome
- 刊名：Leukemia Research
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：48
- 期：Complete
- 页码：62-72
- 全文大小：1462 K
文摘
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New functional polymorphisms (FPs) in DSB repair genes on MDS patients are proposed.
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FPs probably alters the mRNA expression level of the DSB repair genes on MDS.
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FPs are important in the maintenance of genomic instability in MDS.