Dextran sulfate sodium-induced acute experimental colitis in C57BL/6 mice is mitigated by selenium
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- 作者：Lixuan Sanga ; b ; sanglixuan2008@163.com" class="auth_mail" title="E-mail the corresponding author ; Bing Changc ; cb000216@163.com" class="auth_mail" title="E-mail the corresponding author ; Junfeng Zhua ; zjf0709@126.com" class="auth_mail" title="E-mail the corresponding author ; Fangli Yanga ; yfl8412@163.com" class="auth_mail" title="E-mail the corresponding author ; Yan Lia ; licaorenyanyan@163.com" class="auth_mail" title="E-mail the corresponding author ; Xuefeng Jianga ; cmujxf@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Xun Suna ; wsunxun1220@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Changlong Lua ; cllu@mail.cmu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Danan Wanga ; wangdanan1972@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Inflammatory bowel disease ; DSS-induced colitis ; Sodium selenite
- 刊名：International Immunopharmacology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：39
- 期：Complete
- 页码：359-368
- 全文大小：1911 K
文摘
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Selenium pretreatment significantly attenuated the experimental colitis.
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Selenium pretreatment restored interleukin-10 excretion, as well as reducing the levels of interferon-γ and interleukin-17A.
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Selenium corrected DSS-induced imbalance of Th1-Th17/Treg cells.