Evaluation of two strains of Marek's disease virus serotype 1 for the development of recombinant vaccines against very virulent infectious bursal disease virus
We constructed two recombinant vaccines against IBDV based on two MDV1 strains. The two recombinant MDVs exhibited different replication properties. The r814-VP2 virus expressed higher levels of VP2 than rLMS△Meq-VP2. The r814-VP2 virus induced stronger antibody responses against IBDV in chickens. The r814-VP2 vaccine provided full protection against vvIBDV in chickens.