Donor-Derived Natural Killer Cell Infusion after Human Leukocyte Antigen-Haploidentical Hematopoietic Cell Transplantation in Patients with Refractory Acute Leukemia
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- 作者：Inpyo Choi1 ; ipchoi@kribb.re.kr" class="auth_mail" title="E-mail the corresponding author ; Suk Ran Yoon1 ; Soo-Yeon Park1 ; Hanna Kim1 ; Sol-Ji Jung1 ; You-Lee Kang1 ; Je-Hwan Lee2 ; Jung-Hee Lee2 ; Dae-Young Kim2 ; Jae-Lyun Lee2 ; Han-Seung Park2 ; Eun-Ji Choi2 ; Young-Shin Lee2 ; Young-A. Kang2 ; Mijin Jeon2 ; Miee Seol2 ; Seunghyun Baek2 ; Sung-Cheol Yun3 ; Hwa Jung Kim3 ; Kyoo-Hyung Lee2 ; khlee2@amc.seoul.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Donor natural killer (NK) cell infusion ; HLA-haploidentical hematopoietic cell transplantation ; Acute myelogenous leukemia
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：22
- 期：11
- 页码：2065-2076
- 全文大小：809 K
文摘
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Early additional donor natural killer cell infusion after HLA-haploidentical hematopoietic cell transplantation is not associated with an enhanced antileukemia effect
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Early donor natural killer cell infusion after HLA-haploidentical hematopoietic cell transplantation is associated with significant toxicities related to cytokine release
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Higher NKp30 expression on donor natural killer cells is an independent predictor for higher complete remission and less leukemia progression after HLA-haploidentical hematopoietic cell transplantation and donor natural killer cell infusion