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Dynamic Transport and Cementation of Skeletal Elements Build Up the Pole-and-Beam Structured Skeleton of Sponges
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Live imaging shows dynamic transport and assembly of spicules in E. fluviatilis

Newly discovered “transport cells” carry and finally push spicules through epithelia

Raised-up spicules are cemented by collagen expressed in basal epithelial cells

Iteration of “transport-pierce-raise up-cementation” constructs the skeleton

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