Genome variability of foot-and-mouth disease virus during the short period of the 2010 epidemic in Japan

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• 作者：Tatsuya Nishi ; Manabu Yamada ; Katsuhiko Fukai ; Nobuaki Shimada ; Kazuki Morioka ; Kazuo Yoshida ; Kenichi Sakamoto ; Toru Kanno ; Makoto Yamakawa ; ^{yamato@affrc.go.jp}
• 关键词：Foot-and-mouth disease virus ; Genome variability ; Comparative analysis
• 刊名：Veterinary Microbiology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：199
• 期：Complete
• 页码：62-67
• 全文大小：623 K
• 卷排序：199

文摘

Genome dynamics of FMDV over a limited scale of sporadic epidemic was analyzed. Initial FMDV was suggested to be introduced into Japan via single introduction. Generation of an extensive mutant virus was prevented by rapid eradication strategy. VP4 and 2C were highly conserved and VP2 and VP1 were variable in the epidemic.