Cytogenotoxicity of selected organophosphate insecticides on HaCaT keratinocytes and NL-20 human bronchial cells
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- 作者：Eduardo Arteaga-Gó ; meza ; Alejandra Rodrí ; guez-Levisb ; Josefina Corté ; s-Eslavac ; Francisco Arenas-Huerteroa ; Rafael Valencia-Quintanad ; Sandra Gó ; mez-Arroyoc ; slga@atmosfera.unam.mx" class="auth_mail" title="E-mail the corresponding author
- 关键词：Organophosphorus insecticides ; Comet assay ; Cell viability ; Genotoxicity ; Cell death
- 刊名：Chemosphere
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：145
- 期：Complete
- 页码：174-184
- 全文大小：3308 K
文摘
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Four organophosphates were assayed in human cells through viability, genotoxicity and cell death.
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Bronchial and queratinocytes cells showed different sensitivity to genotoxicity of insecticides.
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Viability decreased in both cell lines.
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Ultra structural analysis of cells did not showed changes indicative of cell death by apoptosis.