Comparative genomics analysis of a series of Yarrowia lipolytica WSH-Z06 mutants with varied capacity for α-ketoglutarate production
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- 作者：Weizhu Zenga ; Fang Fanga ; b ; Song Liua ; b ; Guocheng Dua ; b ; Jian Chena ; b ; Jingwen Zhoua ; b ; zhoujw1982@jiangnan.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Yarrowia lipolytica ; α-Ketoglutarate ; High-throughput screening ; Carboxylic acid ; Keto acid ; Genomics sequencing
- 刊名：Journal of Biotechnology
- 出版年：2016
- 出版时间：10 December 2016
- 年：2016
- 卷：239
- 期：Complete
- 页码：76-82
- 全文大小：668 K
文摘
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High-throughput screening combined with random mutagenesis screened varied mutants.
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Comparative genomic analysis was performed to identify gene variation.
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Partial mechanisms of α-KG accumulation were demonstrated in Y. lipolytica mutants.