Combined treatment with flap amputation, phototherapeutic keratectomy, and collagen crosslinking in severe intractable post-LASIK atypical mycobacterial infection with corneal melt

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• 作者：George D. Kymionis ; MD ; PhD ; ^{kymionis@med.uoc.gr} ; Vardhaman P. Kankariya ; MD ; Georgios A. Kontadakis ; MD ; MSc
• 刊名：Journal of Cataract and Refractive Surgery
• 出版年：2012
• 出版时间：April, 2012
• 年：2012
• 卷：38
• 期：4
• 页码：713-715
• 全文大小：229 K

文摘

| Figures/TablesFigures/Tables | ReferencesReferencesA 23-year-old woman was referred for management of intractable post-laser in situ keratomileusis (LASIK) keratitis due to atypical mycobacteria in the left eye. Corrected distance visual acuity was 20/20 in the right eye and counting fingers at 3 meters in the left eye. Slitlamp examination revealed multiple infiltrates in the flap interface and severe corneal stromal melting with thinning. Despite maximum antibiotic therapy for 7 days, the keratitis continued to worsen. A penetrating keratoplasty (PKP) was scheduled. While waiting for a corneal graft, corneal collagen crosslinking (CXL) with riboflavin and ultraviolet-A was proposed as an alternative treatment. Flap amputation and limited phototherapeutic keratotomy (PTK) (10 ¦Ìm) were also performed. One week postoperatively, all infiltrates and stromal edema had resolved. At 3 months, the uncorrected distance visual acuity improved to 20/35. Corneal crosslinking after flap amputation and limited PTK was an effective treatment for severe intractable post-LASIK keratitis with corneal melting and obviated PKP.

Financial Disclosure

No author has a financial or proprietary interest in any material or method mentioned.