Metabolic engineering of Yarrowia lipolytica to produce chemicals and fuels from xylose
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- 作者：Rodrigo Ledesma-Amaro
- 关键词：Yarrowia lipolytica ; Xylose ; Microbial oils ; Metabolic engineering ; Lignocellulosic materials ; Synthetic biology
- 刊名：Metabolic Engineering
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：38
- 期：Complete
- 页码：115-124
- 全文大小：1066 K
文摘
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- <p id="p0005">The overexpressions of heterologous XR and XDH and endogenous XK allow good growth in xylose.p>
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- <p id="p0010">Further engineered strains boosted lipid accumulation in xylose as sole carbon source.p>
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- <p id="p0015">Bioreactor experiments with xylose and glycerol as co-substrates produced 50 g/L of lipids.p>
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- <p id="p0020">Bioreactor experiments in specific conditions produced 80 g/L of citric acid from xylose.p>
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