The mechanism underlying Ler-mediated alleviation of gene repression by H-NS

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• 作者：Minsang Shin <sup>shinms@knu.ac.krsup>
• 关键词：H-NS ; Ler ; Anti-repressor ; LEE (locus of enterocyte effacement)
• 刊名：Biochemical and Biophysical Research Communications
• 出版年：2017
• 出版时间：29 January 2017
• 年：2017
• 卷：483
• 期：1
• 页码：392-396
• 全文大小：796 K
• 卷排序：483

文摘

H-NS specifically represses LEE5 promoter activity and Ler alleviates the repression by H-NS. Binding affinity of Ler to the LEE5 promoter DNA is about 40 folds greater than that of H-NS. Ler binding can remove H-NS bound to the same sites on LEE5 promoter region.