Glioma cell dispersion is driven by α5 integrin-mediated cell-matrix and cell-cell interactions
详细信息 查看全文
- 作者：Anne-Florence Blandina ; Fanny Nouleta ; Guillaume Rennera ; Marie-Cé ; cile Merciera ; Laurence Chouliera ; Romain Vauchellesa ; Philippe Rondea ; Franck Carreirasb ; Nelly Etienne-Sellouma ; d ; Gyorgy Verebc ; Isabelle Lelong-Rebela ; Sophie Martina ; Monique Dontenwilla ; Maxime Lehmanna ; Maxime.lehmann@unistra.fr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Glioblastoma ; Integrin ; Fibronectin ; Focal adhesion kinase ; Migration
- 刊名：Cancer Letters
- 出版年：2016
- 出版时间：1 July 2016
- 年：2016
- 卷：376
- 期：2
- 页码：328-338
- 全文大小：4072 K
文摘
- •
α5 integrin is involved in cell–cell interaction in glioma cells.
- •
Glioma dissemination is tuned by opposite cell–cell and cell/matrix interactions.
- •
α5 and pFAK-Tyr397 do not colocalize at cell–cell adhesion sites.
- •
α5 may trigger different intracellular signals in tumor mass or in migrating cells.
© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号 地址：北京市海淀区学院路29号 邮编：100083 电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700 |