A supramolecular material for dual-modal imaging and targeted cancer therapy

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• 作者：Shanyue Guan^a ; ^b ; Ruizheng Liang^a ; ^{liangruizheng2000@163.com} ; Chunyang Li^a ; Min Wei^a ; ^{weimin@mail.buct.edu.cn}
• 关键词：Supramolecular ; Dual-modal imaging ; Chemotherapy
• 刊名：Talanta
• 出版年：2017
• 出版时间：1 April 2017
• 年：2017
• 卷：165
• 期：Complete
• 页码：297-303
• 全文大小：984 K
• 卷排序：165

文摘

A supramolecular material was prepared by the co-intercalation of FA and DOX into the gallery of Gd3+-doped LDHs. This supramolecular agent was proved to exhibit excellent MRI and FI behavior, as well as chemotherapy toward cancer. The co-intercalated FA enables an efficient and selective drug delivery with good specificity. This work provides a facile approach for the fabrication of a drug formulation with dual-modal imaging and targeted therapy.