The association between availability of serotonin transporters and time to relapse in heroin users ¡ª A two-isotope SPECT small sample pilot study
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- 作者：Shih-Hsien Lin ; Kao Chin Chen ; Sheng-Yu Lee ; Wei Jen Yao ; Nan-Tsing Chiu ; I Hui Lee ; Po See Chen ; Tzung Lieh Yeh ; Mei-Hsiu Liao ; Ru-B ; Lu ; Yen Kuang Yang
- 关键词：Dopamine transporter ; Heroin ; Relapse ; Serotonin transporter
- 刊名：European Neuropsychopharmacology
- 出版年：2012
- 出版时间：September, 2012
- 年：2012
- 卷：22
- 期：9
- 页码：647-650
- 全文大小：342 K
文摘
Neuroimaging evidence supporting an association between either dopamine or serotonin and time to relapse of heroin users is limited. In this two-isotope SPECT small sample (N = 9) pilot study, the relationship between the availability of serotonin transporter (SERT) and dopamine transporter (DAT) and the relapse of heroin users was investigated. A significant negative association between SERT availability and time to relapse among those who relapsed (N = 7) was found.