Nicotine may affect the secretion of adipokines leptin, resistin, and visfatin through activation of KATP channel
详细信息 查看全文
- 作者：Xiao-Jun Bai ; Ph.D. ; M.D.a ; Li-Hong Fan ; Ph.D. ; M.D.a ; Doc_fanlihong@126.com" class="auth_mail" title="E-mail the corresponding author ; Ying He ; M.M.b ; Jie Ren ; M.Ma ; Wei Xu ; Ph.D. ; M.D.a ; Qi Liang ; M.M.a ; Hong-Bing Li ; M.M.a ; Jian-Hua Huo ; Ph.D. ; M.D.a ; Ling Bai ; Ph.D. ; M.D.a ; Hong-Yan Tian ; Ph.D. ; M.D.a ; Fen-Ling Fan ; Ph.D. ; M.D.a ; Ai-Qun Ma ; Ph.D. ; M.D.a
- 关键词：Adipokines ; Smoking ; KATP channel ; Adipocytes
- 刊名：Nutrition
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：32
- 期：6
- 页码：645-648
- 全文大小：306 K
文摘
- •
Serum leptin, resistin, and visfatin were significantly upregulated in male smokers.
- •
Nicotine treatment increased leptin, resistin, and visfatin secretion in 3T3-L1 adipocytes.
- •
The resistin and visfatin secretion was reduced by KATP channel inhibitor, but leptin secretion was not changed.
- •
Nicotine might influence secretion of adipokines through KATP channel.