Tissue-specific mRNA expression profiles of porcine Toll-like receptors at different ages in germ-free and conventional pigs
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- 作者：Lulu Shao ; David D. Fischer ; Sukumar Kandasamy ; Linda J. Saif ; saif.2@osu.edu" class="auth_mail" title="E-mail the corresponding author ; Anastasia N. Vlasova ; vlasova.1@osu.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：DCs ; dendritic cells ; GF ; germ-free ; IFN ; interferon ; IL-4 ; interleukin 4 ; MAMPS ; microbe-associated molecular patterns ; MLNs ; mesenteric lymph nodes ; MNCs ; mononuclear cells ; PRR ; pattern recognition receptor ; PP ; Peyer&rsquo ; s patches ; SLE ; systemic lupus erythematosus ; TLRs ; Toll-like receptors
- 刊名：Veterinary Immunology and Immunopathology
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：171
- 期：Complete
- 页码：7-16
- 全文大小：2109 K
文摘
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Systematically assess porcine TLRs 1–10 mRNA expression profiles.
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Splenic and ileal mononuclear cells have different TLR expression profiles.
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Colostrum/breast milk and commensal microbiota affect innate immunity development.