Porcine deltacoronavirus induces apoptosis in swine testicular and LLC porcine kidney cell lines in vitro but not in infected intestinal enterocytes in vivo
详细信息 查看全文
- 作者：Kwonil Jung ; jung.221@osu.edu" class="auth_mail" title="E-mail the corresponding author ; Hui Hu ; Linda J. Saif ; saif.2@osu.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Coronavirus ; Porcine deltacoronavirus ; Cell death ; Necrosis ; Apoptosis ; Virus ; Pig
- 刊名：Veterinary Microbiology
- 出版年：2016
- 出版时间：15 January 2016
- 年：2016
- 卷：182
- 期：Complete
- 页码：57-63
- 全文大小：1453 K
文摘
- •
The mechanisms of PDCoV induced cell death in vivo and in vitro were unknown.
- •
No PDCoV-infected enterocytes in vivo showed positive TUNEL staining.
- •
TUNEL-positive signals (apoptotic nuclear fragmentation) were found in infected LLC-PK and ST cells that also showed cytopathic effects.
- •
PDCoV does not induce apoptosis in infected enterocytes in vivo, but in LLC-PK and ST cells in vitro.
© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号 地址：北京市海淀区学院路29号 邮编：100083 电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700 |