Goblet cell depletion in small intestinal villous and crypt epithelium of conventional nursing and weaned pigs infected with porcine epidemic diarrhea virus
Goblet cells secret mucins to form intestinal mucus layers Alcian blue or Periodic-Acid-Schiff staining was used to detect goblet cells. PEDV infection resulted in significantly reduced numbers of intestinal goblet cells. During acute PEDV infection, goblet cell mucins in the small intestine may be decreased.