Rats received fruit and vegetable (FV) juice dietary intervention.
Serum from FV juice treated rat was collected and used for cell culture in vitro.
PC12 cells pretreated with H2O2 were used for oxidative damage model in vitro.
Serum from FV juice treated rat protects PC12 cells from oxidative damage.
Multiple antioxidants contributed to the neuron protective effects of FV-rich diet.