Early protein ORF086 is an effective vaccine candidate for infectious spleen and kidney necrosis virus in mandarin fish Siniperca chuatsi
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- 作者：Xiaozhe Fua ; b ; Ningqiu Lia ; b ; liningq@126.com" class="auth_mail" title="E-mail the corresponding author ; Qiang Lina ; b ; Huizhi Guoa ; b ; Lihui Liua ; b ; Zhibin Huanga ; Shuqin Wua ; b
- 关键词：Siniperca chuatsi ; Infectious spleen and kidney necrosis virus ; ORF086 ; Vaccine
- 刊名：Fish & Shellfish Immunology
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：46
- 期：2
- 页码：200-205
- 全文大小：687 K
文摘
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The recombinant protein and DNA vaccine were generated basing on ORF086 gene of ISKNV from Mandarin fish (Siniperca chuatsi).
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The ORF086 protein vaccine could protection against ISKNV challenge.
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The pcDNA086 DNA vaccine could up-regulate the higher expression of immune related genes.
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