A fluorescent imaging assay of cast in renal disease based on graphene quantum dots and Fe3O4 nanoparticles
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- 作者：Dongneng Jiang ; Danni Ni ; Fei Liu ; Liqun Zhang ; Linlin Liu ; Xiaoyun Pu ; xqyyjyk@foxmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Renal disease ; Laboratory diagnosis ; Cast ; Graphene quantum dots ; Fluorescent imaging
- 刊名：Clinica Chimica Acta
- 出版年：2016
- 出版时间：15 February 2016
- 年：2016
- 卷：454
- 期：Complete
- 页码：94-101
- 全文大小：1589 K
文摘
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A specific fluorescent probe was constructed based on graphene quantum dots (GQDs) and Fe3O4 nanoparticles.
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A cast-targeted fluorescent imaging assay was developed for laboratory diagnosis of renal disease.
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It could detect the common types of casts (including RBC, WBC, fatty and granular casts) in clinical specimen.
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It's a sensitive and specific assay of casts.