Nitrated apolipoprotein AI/apolipoprotein AI ratio is increased in diabetic patients with coronary artery disease
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- 作者：Xueying Chena ; b ; Ahmed Bakillaha ; Liye Zhoua ; Xiaoyue Pana ; Florian Hoepfnerc ; Marrit Jacobc ; Xian-Cheng Jianga ; f ; Jason Lazare ; Axel Schlittc ; d ; M.Mahmood Hussaina ; f ; g ; Mahmood.hussain@downstate.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Apolipoprotein AI ; Lipoproteins ; Diabetes ; Cardiovascular disease
- 刊名：Atherosclerosis
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：245
- 期：Complete
- 页码：12-21
- 全文大小：585 K
文摘
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There are significant amounts of nitrated apoAI in the plasma of coronary artery disease patients.
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NT-apoAI/apoAI ratio is significantly higher in diabetes versus non-diabetic patients.
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This ratio is negatively correlated with macrophage cholesterol efflux independent of apoAI.