Simple alumina-mediated synthesis of 2-(2-hydroxypropan-2-yl)benzofuran-3(2H)-ones
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- 作者：Lizhen Fang ; 2002flz@163.com" class="auth_mail" title="E-mail the corresponding author ; Lili Han ; Saisai Liu ; Huanhuan Li
- 关键词：Aldol reaction ; 2-(2-Hydroxypropan-2-yl)benzofuran-3(2H)-one ; Alumina
- 刊名：Tetrahedron Letters
- 出版年：2016
- 出版时间：27 July 2016
- 年：2016
- 卷：57
- 期：30
- 页码：3315-3317
- 全文大小：2683 K
文摘
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The Aldol condensation catalyzed by basic Al2O3 was developed.
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The 10.0 equiv of Al2O3 was the optimum amount.
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The electro-withdrawing or big hindrance of the substrates disfavored the reaction.
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The larger-scale applications and the recycled Al2O3 could be conducted.
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