Molecular characterization and expression analysis of toll-like receptor 2 in response to bacteria in silvery pomfret intestinal epithelial cells
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- 作者：Quanxin Gaoa ; Yingping Xiaob ; Chenjie Zhanga ; Minghua Mina ; Shiming Penga ; shiming.peng@163.com" class="auth_mail" title="E-mail the corresponding author ; Zhaohong Shia ; shizhh@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Toll-like receptor 2 ; Silvery pomfret ; Molecular cloning ; Expression modulation
- 刊名：Fish & Shellfish Immunology
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：58
- 期：Complete
- 页码：1-9
- 全文大小：2448 K
文摘
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The complete cDNA sequence of silvery pomfret TLR2 is 2932 bp, containing an open reading frame (ORF) of 2469 bp.
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Silvery pomfret TLR2 has a high sequence homology with Oplegnathus fasciatus, Epinephelus coioide and Larimichthys crocea.
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TLR2 from the silvery pomfret has the typical structural features of proteins that belong to the TLR family, including one transmembrane domain, eleven LRRs, and oneTIR.
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TLR2 might play a vital role in the L. plantarum and C. butyricum-mediated immune response.
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