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Molecular mechanisms controlling synaptic recruitment of GluA4 subunit-containing AMPA-receptors critical for functional maturation of CA1 glutamatergic synapses
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文摘

PKA activation leads to synaptic unsilencing via insertion of GluA4.

This depends on a novel mechanism involving the extreme C-terminal end of GluA4.

Absence of GluA4 causes delayed postnatal maturation of AMPA transmission.

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