Peripheral whole blood microRNA alterations in major depression and bipolar disorder
详细信息 查看全文
- 作者：Elisabetta Maffiolettia ; 1 ; Annamaria Cattaneob ; c ; 1 ; Gianluca Rossod ; Giuseppe Mainad ; Carlo Maja ; Massimo Gennarellia ; e ; Daniela Tarditof ; Luisella Bocchio-Chiavettoa ; g ; lbocchio@fatebenefratelli.eu" class="auth_mail" title="E-mail the corresponding author
- 关键词：MicroRNA ; Major depression ; Bipolar disorder ; Blood ; Biomarker ; Let-7
- 刊名：Journal of Affective Disorders
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：200
- 期：Complete
- 页码：250-258
- 全文大小：780 K
文摘
- •
5 miRNAs are specifically altered in the blood of MD patients.
- •
5 miRNAs are specifically altered in the blood of BD patients in a depressive phase.
- •
2 miRNAs are commonly altered in both the mood disorders.
- •
The dysregulated miRNAs potentially affect the expression of brain-relevant genes.