Mineralization Effect of Hyaluronan on Dental Pulp Cells via CD44
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- 作者：Kuan-Liang Chen ; DDS ; MS&lowast ; ; &dagger ; ; Ying-Yi Yeh ; MS&Dagger ; ; Jrhau Lung ; PhD§ ; ; Yu-Chi Yang ; MS&Dagger ; ; Kuo Yuan ; DDS ; PhD&Dagger ; ; || ; kuoyuan.tw@yahoo.com.tw" class="auth_mail" title="E-mail the corresponding author
- 关键词：CD44 ; dental pulp ; hyaluronan ; mineralization ; odontoblast ; PCR array
- 刊名：Journal of Endodontics
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：42
- 期：5
- 页码：711-716
- 全文大小：1215 K
文摘
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How hyaluronan regulated the mineralization of dental pulp cells was investigated.
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ALPL, BMP7, and Col15A1 were upregulated via the hyaluronan-CD44 pathway.
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The staining pattern of BMP7 was very similar to that of CD44 on tooth sections.
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The findings may help develop new strategies in regenerative endodontics.