What does the MADRS mean? Equipercentile linking with the CGI using a company database of mirtazapine studies

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• 作者：Stefan Leucht^a ; ^{Stefan.Leucht@tum.de} ; Hein Fennema^b ; Rolf R. Engel^c ; Marion Kaspers-Janssen^d ; Peter Lepping^e ; ^f ; Armin Szegedi^g
• 关键词：Montgomery Asberg Depression Rating Scale (MADRS) ; Clinical Global Impression (CGI) ; Clinical relevance ; Major depression ; Remission ; Response ; Equipercentile linking
• 刊名：Journal of Affective Disorders
• 出版年：2017
• 出版时间：1 March 2017
• 年：2017
• 卷：210
• 期：Complete
• 页码：287-293
• 全文大小：607 K
• 卷排序：210

文摘

The results provides guidance for clinicians and researchers in their interpretation MADRS scores. We confirm the validity of the commonly used measures for response in major depressive disorder trials. Our analysis suggests that a MADRS total score of <8 indicates remission.