Anti-JC virus seroprevalence in a Spanish multiple sclerosis cohort: JC virus seroprevalence in Spain
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- 作者：Yolanda Aladroa ; yolanda.aladro@salud.madrid.org" class="auth_mail" title="E-mail the corresponding author ; Rodrigo Terreroa ; Marta Cerezoa ; Ricardo Ginestalb ; Lucí ; a Ayusoc ; Virginia Meca-Lallanad ; Jorge Millá ; ne ; Laura Borregof ; Marisa Martinez-Giné ; sg ; Luisa Rubioc ; Clara de André ; sg ; Ambrosio Mirallesh ; Cristina Guijarroi ; Elena Rodrí ; guez-Garcí ; aj ; José ; Manuel Garcí ; a-Dominguezk ; Carmen Muñ ; oz-Ferná ; ndezl ; Carlos Ló ; pez de Silanesm ; Mayra Gó ; mezn ; Israel Thuissardo ; Marí ; a Cerdá ; np ; q ; Itziar Palmí ; d ; Luis Felipe Dí ; az-Garzó ; ni ; Jose Meca-Lallanap ; q
- 关键词：Anti-JCV antibodies ; Seroprevalence ; Multiple sclerosis ; Spain
- 刊名：Journal of the Neurological Sciences
- 出版年：2016
- 出版时间：15 June 2016
- 年：2016
- 卷：365
- 期：Complete
- 页码：16-21
- 全文大小：236 K
文摘
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The seroprevalence of anti-JCV antibodies in Spanish MS patients' cohort was between 55.3 and 60.5%.
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Seroprevalence JCV only increased with age and when 2nd generation ELISA was employed.
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The seroconversion rate was 7% per year.
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Changes in serostatus were observed in 8% of our patients.
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Fluctuations on serological status were associated with antibody index near to assay's cut-off.