Catalytic asymmetric synthesis of cyclic α-alkyl-amino acid derivatives having a tetrasubstituted α-carbon

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• 作者：Yong-Gang Wang ; Haruka Mii ; Taichi Kano ; Keiji Maruoka
• 关键词：Asymmetric synthesis ; Amino acid ; Phase-transfer ; Alkylation ; Cyclic
• 刊名：Bioorganic and Medicinal Chemistry Letters
• 出版年：2009
• 出版时间：15 July 2009
• 年：2009
• 卷：19
• 期：14
• 页码：3795-3797
• 全文大小：490 K

文摘

Catalytic asymmetric synthesis of various cyclic α-alkyl-amino acid derivatives having a tetrasubstituted α-carbon has been accomplished by the utilization of phase-transfer alkylation of α-alkyl-amino acid derivatives.