Modulation of the cellular content of metabolites in adipocytes by insulin
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- 作者：Yuhang Qiao ; Shozo Tomonaga ; Tohru Matsui ; Masayuki Funaba ; mfunaba@kais.kyoto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：Insulin ; Adipocyte ; Citric acid ; Succinic acid ; Fumaric acid ; Malic acid ; Metabolome
- 刊名：Molecular and Cellular Endocrinology
- 出版年：2016
- 出版时间：15 March 2016
- 年：2016
- 卷：424
- 期：Complete
- 页码：71-80
- 全文大小：1997 K
文摘
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Insulin induced accumulation of metabolites from citric acid cycle in adipocytes.
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Insulin generally decreased free amino acids in adipocytes.
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Insulin regulates metabolite content via the PI 3-kinase and ERK pathways.
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Insulin stimulated oscillations of metabolites with a 2-h cycle.