Long-Term Safety Outcomes in Patients with Hematological Malignancies Undergoing Autologous Hematopoietic Stem Cell Transplantation Treated with Palifermin to Prevent Oral Mucositis
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- 作者：Patrick J. Stiff1 ; pstiff@lumc.edu" class="auth_mail" title="E-mail the corresponding author ; Mika Leinonen2 ; 3 ; Torbjö ; rn Kullenberg2 ; Mattias Rudebeck2 ; Maarten de Chateau2 ; Ricardo Spielberger4 ; 5
- 关键词：Palifermin ; Hematopoietic stem cell transplantation ; Second malignancies ; Mucositis
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：22
- 期：1
- 页码：164-169
- 全文大小：829 K
文摘
We evaluated long-term safety outcomes (up to 15 years) of palifermin in hematopoietic stem cell transplantation patients
We found comparable overall survival between palifermin and placebo groups
The data showed comparable progression-free survival rate between palifermin and placebo groups
There were no differences found in secondary hematological malignancies between the 2 groups
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